NRAKG (Nicotinamide Riboside Alpha-Ketoglutarate)
The ultimate synergistic combination leveraging alpha-ketoglutarate’s metabolic benefits with NR’s proven NAD⁺ boosting properties. Designed for comprehensive cellular support and advanced anti-aging formulations.
A revolutionary combination targeting multiple longevity pathways simultaneously. NRAKG combines the proven NAD⁺ boosting power of NR with the cellular energy and anti-aging benefits of alpha-ketoglutarate for comprehensive longevity support.
Complex Profile
Active Components:
NR + AKG
Ratio:
Optimized 1:2
Molecular Weight:
441.35 g/mol
Purity:
≥98.0% combined
Solubility:
Highly water soluble
Appearance:
White to off-white powder
Stability:
2 years (proper storage)
Synergy:
Validated
Comprehensive Pathway Coverage
NRAKG targets multiple biological pathways critical for healthy aging and cellular longevity
| Biological Pathway | Active Component | Primary Benefit |
|---|---|---|
|
NAD⁺ Synthesis |
NR Component |
Cellular energy restoration |
|
Krebs Cycle |
α-KG Component |
Mitochondrial optimization |
|
Protein Synthesis |
α-KG Component |
Cellular repair enhancement |
|
Epigenetic Regulation |
Combined Action |
Gene expression optimization |
Synergistic Science
NRAKG combines two powerful anti-aging compounds to target multiple cellular pathways simultaneously,
providing comprehensive support beyond individual components.
Nicotinamide Riboside
-
NAD⁺ precursor via salvage pathway
-
Enhances cellular energy production
-
Supports DNA repair mechanisms
-
Activates longevity pathways
Alpha-Ketoglutarate
-
Key metabolite in TCA cycle
-
Supports cellular metabolism
-
Promotes protein synthesis
-
Anti-aging epigenetic effects
Synergistic Benefits
Enhanced Energy
Combined NAD⁺ and TCA cycle optimization
Cellular Protection
Multi-pathway approach to cellular health
Longevity Support
Targets multiple hallmarks of aging
Research Foundation
Preclinical studies demonstrate enhanced efficacy of the combined approach
Metabolic Enhancement Study
+147%
NAD⁺ elevation vs. baseline
+89%
Mitochondrial respiration
*Cell culture study, 48-hour treatment
Longevity Pathway Activation
+234%
SIRT1 activity increase
+156%
AMPK phosphorylation
*Compared to individual components
Cellular Health Markers
-67%
Oxidative stress markers
+123%
Cellular viability
*Stress challenge model
Comprehensive Benefits
Validated health benefits across multiple physiological systems
Metabolic Synergy
Combines NAD⁺ boosting with alpha-ketoglutarate benefits
Anti-Aging Compound
Targets multiple hallmarks of aging simultaneously
Enhanced Cellular Energy
Supports both NAD⁺ and TCA cycle optimization
Comprehensive Support
Broad-spectrum cellular health and longevity benefits
Enhancement of SIRT1 Gene Expression in Zebrafish
Sirt1 gene serves to repair DNA and regulate genes for metabolism. The Sirt1 gene expression enhancing rate of Senolyte™ NRAKG sample in zebrafish was 14%, nearly 50% improvement via NRCl & Ca-AKG, at the test concentration of 0.025g/L.
These findings demonstrate that Senolyte™ NRAKG could significantly enhance Sirt1 gene expression in zebrafish and outperforms NRCL and AKGCa mixture, suitable for applications targeting healthy aging and metabolic resilience.
Quality Certifications
Comprehensive quality assurance and regulatory compliance for global markets
GRAS Certified
Non-GMO Verified
Vegan Compatible
Halal Certified
ISO 22000
GMP Compliant
Application Forms
Versatile ingredient suitable for various delivery systems and formulation types.
- Longevity Formulas
- Performance Nutrition
- Anti-Aging Products
- Metabolic Health
- Cellular Support
- Premium Blends
Ready to Unlock Synergistic Anti-Aging Power of NRAKG ?
Formulate with the most advanced combination for comprehensive cellular support and longevity.
